Title Page Title: Recombinant human deoxyribonuclease for the treatment of acute asthma in children
نویسندگان
چکیده
Department of pediatric pulmonology, Erasmus MC-Sophia Children’s Hospital, Rotterdam, the Netherlands. Department of pediatrics, Medisch Centrum Rijnmond Zuid, Rotterdam, the Netherlands; Department of pediatrics, Albert Schweitzer Hospital, Dordrecht, the Netherlands; Department of pediatrics, Amphia Hospital, Breda, the Netherlands; Department of pediatrics, HagaTeaching Hospital/Juliana Children's Hospital The Hague, the Netherlands; Department of pediatrics, Reinier de Graaf Gasthuis, Delft, the Netherlands; Department of pediatrics, Catharina Hospital, Eindhoven, the Netherlands; Department of pediatrics, Sint Franciscus Gasthuis, Rotterdam, the Netherlands; Department of epidemiology and biostatistics, Erasmus MC, Rotterdam, the Netherlands; Department of pediatrics, division of respiratory medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
منابع مشابه
Use of magnesium in moderating tachycardia in acute severe asthma in pregnancy.
1 Sellers WFS. Inhaled and intravenous treatment in acute severe and life-threatening asthma. Br J Anaesth 2013; 110: 183–90 2 Patel A, Harrison E, Durward A, et al. Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment. Br J Anaesth 2000; 84: 505–7 3 Durward A, Forte V, Shemie SD. Resolution of mucus plugging and atelectasis aft...
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BACKGROUND Airway obstruction in acute asthma is the result of airway smooth muscle contraction, inflammation and mucus plugging. Case reports suggest that mucolytic therapy might be beneficial in acute asthma. The aim of this study was to determine the efficacy of the mucolytic drug recombinant human deoxyribonuclease (rhDNase) in addition to standard treatment at the emergency department in c...
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